Insulin antibodies


Suspicion of risk of developing type 1 diabetes (T1D, previously known as insulin-dependent diabetes mellitus, IDDM). The marker may be used for early diagnosis of T1D in both young and old people.


Radioimmunoprecipitation with native antigen. Insulin regulates blood glucose levels and consists of 51 amino acids. 


The result is given as negative or positive with units.


IgG antibodies against insulin are found in T1D but do not occur as often as antibodies to GAD-65 or IA-2. Approximatelly 60% of T1D patients have antibodies againts insulin. When patients are treated with insulin the antibody may be masked by high levels of insulin analouges in patient serum. 

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