SSB/La antibodies

Indication

SSB/La antibodies are included in the analysis ENA screen. See therefore “ENA screen” for indication, method, answer and reference range.

Interpretation

Positive in about 70% of patients with primary Sjögren’s syndrome and in 5-30% of patients with SLE. It usually occurs together with SSA in Sjögren’s syndrome and SLE but may sometimes occur in scleroderma and RA. Isolated occurrence of SSB has been described in primary biliary cirrhosis and autoimmune hepatitis.

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20 years experience