Striated muscle antibodies

Indication

Suspicion of myasthenia gravis and thymoma.

Method

Indirect immunofluorescence.

Answer

The result is given as negative or weak, medium or strong positive after evaluation of the fluorescence intensity.

Interpretation

Autoantibodies to striated muscle are tested in suspicion of myasthenia gravis, and especially in patients who also have thymoma. May be mild positive in chronic muscular diseases such as polymyositis, muscle dystrophy and fibromyalgia.

Antibodies against striated muscle with specificity for Titin are primarily associated with Myasthenia Gravis (MG) with onset after age 50 (late onset MG) but can also be seen at thymoma. Please contact the laboratory if a follow-up analysis of antibodies against Titin is wished.

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Packages and other tests

View other packages Myasthenia gravis (543). View other tests Acetylcholine receptor antibodies, LRP4 antibodies, MuSK antibodies, Ryanodine receptor antibodies, Titin antibodies

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