C1q is the first subcomponent of the C1 complex of the classical pathway of complement activation. Several functions have been assigned to C1q, which include antibody-dependent and independent immune functions, and are considered to be mediated by C1q receptors present on the effector cell surface. There remains some uncertainty about the identities of the receptors that mediate C1q functions. Some of the previously described C1q receptor molecules, such as gC1qR and cC1qR, now appear to have less of a role in C1q functions than in functions unrelated to C1q.

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Packages and other tests

View other packages Complement deficiency (572), Hereditary angioedema (HAE) (571). View other tests C1- inhibitor, C1q antibodies, C3, C4, C3d, C4d, Complement analysis

20 years experience