Zinc transporter 8 (ZnT8) antibodies

Indication

Suspicion of type 1 diabetes (T1D).

Method

Radio immunoprecipitation (RIA).

Answer

Negative, borderline or positive with a ratio.

Interpretation

Antibodies against ZnT8 is an independent marker for type 1 diabetes (T1D) and combined with antibodies against GAD-65, insulin, IA-2 and islet cells it gives an improved diagnostic sensitivity. Anti-ZnT8 antibodies can be associated with different clinical phenotypes of T1D compared to anti-GAD-65 or anti-IA-2 antibodies.

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Reference

Han et. al. Am J Transl Res. 2013. PMID: 23724162

Packages and other tests

View other packages Diabetes (531). View other tests GAD antibodies, IA-2 antibodies, Insulin antibodies, Islet cell antibodies

Acute test