Thrombospondin Type 1 Domain Containing 7A (THSD7A) antibodies


Suspicion of primary membranous nephropathy (PMN), previously idiopathic membranous nephropathy (IMN).


Indirect immunofluorescence (IIF) with THSD7A transfected cells


The result is given as negative or positive. A positive result is followed by a titer.


Antibodies against THSD7A have been reported to occur in about 10% of the anti-PLA2R negative cases with membranous nephropathy (PMN). The antibodies are primarily of IgG4 subclass and seem to have high disease specificity. Antibody titers also appear to be associated with disease activity and follow the degree of proteinuria.

Read more about sampling

Packages and other tests

View other packages Glomerulonephritis (500), Primary Membranous Nephropathy (PMN) (584). View other tests ANA screen (HEp-2 cells), dsDNA antibodies, GBM antibodies (the Goodpasture antigen), MPO-ANCA (capture technique), MPO-ANCA (direct technique), Phospholipase A2 receptor (PLA2R) antibodies, PR3-ANCA (capture technique), PR3-ANCA (direct technique), Streptolysin O antibodies

Acute test